Abnormal bone growth in adults

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A nonhealing fracture, also called a nonunion, occurs when the pieces of a broken bone do not grow back together. Usually, bones start rebuilding immediately after a doctor has aligned the bone fragments and stabilized them into place. This process is called setting the bone. During the following weeks or months, new bone tissue continues to form. As long as the bone fragments receive an adequate supply of blood and nutrients, the new tissue fuses the fragments together into a single bone.
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Bone Tumors

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Fibrous dysplasia - Better Health Channel

Heterotopic ossification is the word used to describe bone that forms in a location where it should not exist. Heterotopic ossification generally means that bone forms within soft tissues, including muscle, ligaments, or other tissues. Often abbreviated "H. Heterotopic bone often forms after surgery, injury, or sometimes for unknown reasons. The most common symptom of heterotopic ossification is stiffness of a joint. Most people who develop heterotopic ossification cannot feel the abnormal bone, but notice the bone growth getting in the way of normal movements. Heterotopic bone often forms around the hip or elbow joints, making bending of these joints difficult.
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Fibrous dysplasia

Two recent studies on a rare genetic disorder that causes excess bone to form have greatly contributed to our understanding of how the disease progresses, and have identified promising treatment options. Fibrodysplasia ossificans progressiva FOP is a debilitating disorder that leads to heterotopic ossification HO , an abnormal process in which extra bone develops outside the skeleton in soft tissues, such as muscles, tendons and ligaments. The mutated gene abnormally activates the BMP pathway, leading to HO episodes, also called flare-ups. The HO lesions eventually result in fused joints and loss of mobility. As the disease progresses, it can cause difficulty breathing and swallowing, and eventually death.
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Osgood-Schlatter disease OSD is swelling and irritation of the growth plate at the top of the shinbone. A growth plate is a layer of cartilage near the end of a bone where most of the bone's growth happens. It is weaker and more at risk for injury than the rest of the bone. OSD typically causes pain and swelling below the kneecap.
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